Showing posts with label steroid creams. Show all posts
Showing posts with label steroid creams. Show all posts

Tuesday, 15 July 2025

Science-Backed Tips for Easing a Psoriasis Flare

From healthcentral.com

Right this way for fast relief of your itchy, painful skin 

Flares are a fact of life with psoriasis, the skin condition that appears as scaly plaques on areas of the body like the scalp, elbows, and knees. Not only can psoriasis flares make people feel self-conscious, “they can be very itchy and uncomfortable for patients to deal with,” says Lauren Penzi, M.D., a board-certified dermatologist in New York City.

Psoriasis flares can describe any time that you’re not in remission, and they can reduce your quality of life, impair your activity, and increase your anxiety, according to a study in the Journal of Psoriasis and Psoriatic Arthritis. And they tend to be a long-term game: If psoriasis plaques are there on Monday, “they’re probably still going to be there on Friday—but maybe they're not as itchy, as white, as flaky, or as bothersome,” says Elizabeth Kiracofe, M.D., a board-certified dermatologist in Chicago. “But they’re still going to be there because psoriasis doesn’t come and go that quickly.”

That’s because psoriasis is a chronic disease that stems from a disruption in the immune system which affects skin cells. This “increases the inflammation that goes on in the body that then signals the skin to make the psoriasis lesions that we see with our eyes,” says Dr. Kiracofe.

The good news? The sooner you can treat a psoriasis flare-up, the faster you’ll get relief—and this is the month to start. Depending on the severity of your psoriasis, you may need to explore long-term options like biologics, a type of medication that works from within the body to control and clear plaques. “A biologic can be part of the marathon plan,” she says.

However, there are steps you can take at home to get relief in the meantime. Here’s what the experts recommend for getting your symptoms under control ASAP.

                                                                                          GettyImages/triocean

Slather Moisturizer Everywhere

Moisturizing is a must for anyone with psoriasis, since it can be associated with a compromised skin barrier—but especially if you’re dealing with a flare. Pro tip: Moisturize your skin from head to toe, not just where you notice an initial plaque. “A common misconception with psoriasis is that you only need to treat the lesions, but in patients who have psoriasis, all of their skin is compromised, and so their barrier is disrupted everywhere,” says Dr. Kiracofe.

She recommends any moisturizer that you can scoop from a tub or squeeze out of a tube, “because that implies it’s a little heavier,” she says. Look for skin-soothing formulas with occlusive ingredients—like oils and butters—as well as ceramides, since these types of lipids can be missing from the skin barrier when it’s compromised.

At night, you can take your skin hydrating game up a notch by topping off areas where plaques appear with wet dressings that can lock in ointments—follow this how-to in order to do it properly.

Target Plaques With Topical Steroids

With moderate to severe psoriasis, systemic meds may be needed to treat the underlying disease. But for immediate plaque-itch relief, topical steroids are your best friend. “Use it twice a day until the plaque is gone, plus two extra days,” says Dr. Kiracofe. “Then we know it’s going to stay gone—versus if you just use it once a day for a few days a week.”

Apply your medication first, and then top it with moisturizer. Most of the prescription topicals prescribed for psoriasis “are stripping of the skin barrier, so they’re dehydrating to the skin,” says Dr. Kiracofe. And when skin is dehydrated, the moisture barrier is more fragile—so using medication alone is “kind of like three steps forward, two steps back,” she says.

Both Dr. Penzi and Dr. Kiracofe agree that if you don’t have prescription-strength topicals on hand, go ahead and use a 1% hydrocortisone cream. It’s not a long-term solution, but it can help you manage your flare until you see a doctor.

And, if you can’t get in with your dermatologist right away, consider seeing your primary care doctor, who can start you off with a prescription for a more powerful topical steroid. And, of course, “we want to make sure that—in addition to whatever active ingredient—we’re still moisturizing the skin as well,” says Dr. Kiracofe.

Apply a Cool Compress

Psoriasis flares can come with intense itchiness and you want to do all you can to prevent yourself from scratching your plaques, since it further traumatizes an already compromised skin barrier.

As you wait for topical formulas to bring healing, apply cool compresses to temporarily calm inflammation and itching, says Dr. Penzi. (If you’re able to make it to the drugstore, she also points to pramoxine as a good, over-the-counter topical anaesthetic that helps numb the skin to control itchiness.) Cooling the skin can actually have a big impact on the intensity of itch; one study found that it acts directly on sensory receptors that oversee itchiness in skin.

Download a Mindfulness App

According to the American Academy of Dermatology Association (AAD), many things can trigger a psoriasis flare, from summertime exposures—such as a sunburn or even sitting in air conditioning—to chronic issues like increased stress. Stress and psoriasis are closely linked; even changing jobs or a breakup out of nowhere can trigger some psoriasis flares, as stress releases hormones like cortisol, which can exacerbate inflammation. For that reason, the skin is often the first place you’ll see signs of stress, says Dr. Kiracofe.

On the bright side: “Anything that can bring down the production of that stress hormone is beneficial,” says Dr. Kiracofe. In fact, she recommends mindfulness apps to her psoriasis patients, asking them to meditate two to three minutes a day. It may also help you fight the urge to scratch, she says. A systematic review of the relationship between mindfulness and psoriasis found that it can in fact be a short-term tool for improving both the severity of psoriasis as well as quality of life (meaning people with psoriasis experience less worry, anxiety, and depression stemming from the condition).

Layer on Extra Protection

Depending on the weather, this might be a good time to spring for long sleeves and pants to protect your skin, since any scratches or even tiny wounds can trigger the development of a new plaque. It’s called the Koebner Phenomenon, where “new psoriasis lesions form on previously unaffected skin due to trauma,” says Dr. Penzi.

So, it’s critical to protect your body from any incidental trauma, according to Dr. Kiracofe. That’s also part of the reason moisturizing is so important: It acts as an extra shield. “If your skin is healthy and moisturized and prepared, that trauma is less likely to have an impact,” she says.

Your Flare Game Plan

Unlike some skin conditions, psoriasis is an autoimmune disease. And, as an immune-mediated problem stemming from within your body, “it generally needs prescription medicines to help solve it” from the inside, says Dr. Kiracofe. Since there is no cure for it (yet), the objective is for psoriasis that’s “well controlled,” as she puts it: “My goal as your doctor is to make sure that psoriasis is no longer the first thing you think about when you get up in the morning.”

So, while these tips can offer quick relief and quell inflammation from the outside, they can’t address the autoimmune disease that’s triggering the plaque-causing inflammation in the first place—which is why it’s worth getting in touch with your doctor if your current treatment plan isn’t cutting it. “There are so many new things that we have to offer in the world of psoriasis—because, frankly, over-the-counter stuff just can't solve the problem,” Dr. Kiracofe says.

https://www.healthcentral.com/condition/psoriasis/science-backed-tips-for-easing-a-psoriasis-flare

Tuesday, 9 July 2024

How to Treat Plaque Psoriasis

From healthcentral.com

From topical ointments to light therapy and systemic meds, these are your options for managing this chronic skin disease 

We’ve come a long way from the days of messy creams and sticky tars for plaque psoriasis treatment. With a new understanding of the cause of psoriasis related to a malfunctioning immune system, treatments are now often focused on targeting the inflammation before it even begins to wreak havoc on the skin. There is no cure for psoriasis, but there are many targeted treatments available that can reduce inflammation and help your skin recover back to its pre-psoriasis state.

                                                                      GettyImages/Tanja Ivanova

Topical Treatments for Plaque Psoriasis

Kurt Ashack, M.D., a dermatologist and assistant professor at the Michigan State University College of Human Medicine in East Lansing, Michigan, says that even with newer, systemic medications, topic treatments still play a major role in psoriasis treatment. “Topical treatments are where I start off therapy with every patient who has a manageable number of plaques without psoriatic arthritis,” he says. Fortunately, there are numerous topical treatments available:

Over-the-Counter (OTC) Topical Nonsteroidals

There are many psoriasis treatments available over the counter (a.k.a. without a doctor’s prescription). According to the American Academy of Dermatology Association, these products work best if you have very mild psoriasis. Some of these treatments include:

  • Anti-itch medication: Calamine Lotion (calamine), Aveno Skin Relief, Gold Bond among others (menthol)

  • Coal tar: Neutrogena T-Gel Therapeutic Shampoo, MG217 Psoriasis Medicated Conditioning Shampoo, among others

  • Moisturisers: CeraVe Psoriasis Cream, CurĂ©l Hydra Therapy Itch Defense, Dermarest Psoriasis Medicated Treatment Gel, among others

  • Salicylic acid: Neutrogena T/Sal, Salicyn and Keralyt

Prescription Topical Steroids

While some steroids (a.k.a. corticosteroids) can be purchased over the counter, others require a prescription. How they are available depends on the strength of the medicine. Steroids are divided into seven different classes, with class I considered the most potent and class VII considered the lowest potency. Even topical steroids come with potential side effects, so only the lowest strength is available over the counter and stronger concentrations will need a doctor’s prescription. You can find topical steroids in different formulations such as ointments, creams, lotions, gels, and foams. Some of the prescription topical steroids include:

  • Bryhali, Lexette, Ultravate (halobetasol)

  • Celestone Soluspan (betamethasone)

  • Clobevate, Clobex, Cormax, among others (clobetasol)

Prescription Topical Non-Steroids

Just as there are newer classes of oral medications available for psoriasis treatment, there are also newer classes of topical non steroid medications. They include:

  • Anthralins: Drithocreme, Psoriatec, Zithranol, among others

  • Calcineurin inhibitors: Elidel (pimecrolimus), Protopic (tacrolimus)

  • Hydrocarbon receptor antagonists: VTAMA (Tapinarof)

  • Phosphodiesterase-4 (PDE4) inhibitors: ZORYVE (Roflumilast)

  • Vitamin A derivatives: Duobril (halobetasol propionate) Soriatane (acitretin), Tazorac (tazarotene)

  • Vitamin D analogsDovonex (calcipotriene), Enstilar (calcipotriene and betamethasone dipropionate), Taclonex (calcipotriene and betamethasone dipropionate), Vectical (calcitriol)

Systemic Treatments for Plaque Psoriasis

As the understanding of psoriasis as a whole-body disease came into focus, so did new choices of skin treatment that worked from the inside out. However, along with those systemic therapies came an increased patient concern around potential new side effects. George Han, M.D., dermatologist at Lenox Hill Hospital in New York City, says he frequently talks with his patients about their side-effect concerns.

“I think the best way to go about tackling side effect questions is to address both the rational concerns and the irrational ones, but separately,” he says. “For the former, we can address rational concerns about treatments with data.” That includes results from clinical trials—most of the medications have at least four to five years of highly scrutinized data, as well as registrational data collected after medicines come to market, Dr. Han explains. “For our newer classes of medicines, the IL-17 and IL-23 inhibitors, thankfully, the safety profiles look very good,” he says. “For example, some medications feature a side-effect profile that is within 1% to 2% of the placebo, at which point it’s hard to say that any side effects are actually due to the medication.”

There are a few specific concerns that are valid. “The IL-17 inhibitor class does have the potential to make inflammatory bowel disease (such as Crohn’s disease) worse, and TNF alpha inhibitors have a slightly higher risk in terms of potential infections and non-melanoma skin cancer,” says Dr. Han. “Outside of these specifics, though, there is no strong data to support our modern treatments having a high risk for any major issues.”

Biologic Treatments for Plaque Psoriasis

The U.S. Food and Drug Administration (FDA) has approved the following biologics to treat adults with psoriasis:

  • Cimzia (certolizumab pegol)

  • Cosentyx (secukinumab)

  • Enbrel (etanercept)

  • Humira (adalimumab)

  • Ilumya (tildrakizumab)

  • Remicade (infliximab)

  • Siliq1 (brodalumab)

  • Skyrizi (risankizumab)

  • Stelara (ustekinumab)

  • Taltz (ixekizumab)

  • Tremfya (guselkumab)

Other Systemic Treatments

Beyond biologics, there are other medications for psoriasis that work throughout the body. Some are more traditional disease modifying antirheumatic medications (DMARDs) and others fall into newer classes of treatments.

  • DMARD: Rheumatrex, Trexall, Otrexup (methotrexate), Arava (leflunomide)

  • Immunosuppressant: Gengraf, Neoral, Sandimmune (cyclosporine)

  • PDE-4 Inhibitor: Otezla (apremilast

  • JAK Inhibitor: Xeljanz and Xeljanz XR (tofacitinib)

Off-Label Systemic Drugs

Sometimes a provider will prescribe a medication that has not been FDA-approved to treat the condition, but it is still known to work well. This is a perfectly legal practice under a doctor’s supervision. Some of the off-label medications for psoriasis include:

  • Arava (leflunomide)

  • Azasan (azathioprine)

  • Cellcept, Myhibbin (mycophenolate mofetil)

  • Envarsus XR, Prograf, Astagraf XL (tacrolimus)

  • Fumaderm (fumaric acid esters)

  • Hydrea, Droxia (hydroxyurea)

  • Sulfasalazine (sulfasalazine)

  • Tabloid (6-thioguanine)

Phototherapy for Plaque Psoriasis

Phototherapy is a type of psoriasis treatment that uses light to help slow the rapidly growing skin cells. There are a variety of light treatments available including:

Ultraviolet Light B (UVB)

UVB therapy involves exposing the impacted skin to one of two types of UVB lights: broad band and narrow band. This treatment usually happens in a doctor’s office for a set length of time over a set schedule, usually two to three times a week, according to the American Academy of Dermatology Association.

Ultraviolet Light A (UVA) and Psoralens

This type of light therapy involves taking medication (psoralens) prior to the therapy to make the skin more sensitive to sunlight. UVA light penetrates deeper into the skin than UVB light and is often used for more severe psoriasis, according to the Mayo Clinic.

Sunlight

Both UVB and UVA are found in sunlight, however, using sunlight to treat psoriasis is not recommended for everyone, advises the National Psoriasis Foundation. Some medications can increase the risk of sunburn, so it is important to check with your provider about how much sun exposure is safe for your skin.

Talking With Your Doctor About Treatment

Even if you have mild psoriasis, appearing on less than 3% of your body, this can still indicate significant inflammation in the body. Whole body inflammation could lead to other diseases, such as cardiovascular disease. That’s why treating your psoriasis is so important. Fortunately, newer classes of medication are quite effective and have a good safety profile. The key is to work closely with your provider to find a treatment that goes along with your lifestyle and helps you feel your best.

https://www.healthcentral.com/condition/psoriasis/plaque-psoriasis-treatment?ap=nl2060&rhid=&mui=&lid=141093361&mkt_tok=NTQxLUdLWi0yNDMAAAGUNuB_NRCLov0F4J7jeDM5VD6FrPSAPDoKGbMh0ZgJzbARcbQdB6d-5fucoFqaWM4RIMjDPrdAPTTijyVzpLgTwLrz7XHO92NRFyLINVSUBKUqLcw

Wednesday, 3 January 2024

Steroid Creams for Psoriasis: What to Know

From healthline.com

Steroid creams, also called topical steroids or corticosteroids, can help treat psoriasis, but long-term use can cause side effects. Here’s what to know about using these creams safely.

Person applies topical medication to psoriasis on knee 2Share on Pinterest
Ternavskaia Olga Alibec/Shutterstock

Topical steroids are anti-inflammatory drugs you apply directly to your skin. These medications are one common treatment for psoriasis, an autoimmune condition where you develop scaly patches, called plaques, across your skin.

Steroid creams can shrink these patches or even help them go away completely. However, these medications can cause side effects if you use them for an extended period, so it’s important to follow any instructions your primary care doctor or dermatologist provides.

Below, get the details on different types of steroid creams, how they work, and precautions to take while using them.

If you have psoriasis, your immune system gets confused and starts attacking your own skin. Antibodies flood the area to defend against the attack, and the surrounding tissue becomes inflamed. You may notice discoloured skin, swelling, pain, and tenderness.

Psoriasis also causes your skin to produce cells faster than the old ones can fall off, which is what creates the plaques of thick and flaking skin.

When you apply a steroid cream, the steroids sink into the layers of your skin and enter various cells.

Topical steroids help treat psoriasis by telling your cells to:

  • stop making so many inflammatory chemicals
  • make more anti-inflammatory chemicals
  • slow down the growth of new skin cells

Because corticosteroids resemble the steroid hormones made by your adrenal glands, the cells accept their instructions as if they came from your own body.

That said, you’ll need to keep applying the cream to replenish the medication in your skin. As the steroids hold off the psoriasis process, the patch should gradually shrink, allowing your skin to heal.

Topical steroids are organised into 7 classes, with class 7 being the mildest and class 1 the strongest. Here are examples of creams you might find in each level:

  • Class 7 (mild): Hydrocortisone (Synacort, Mycort-HC, Cortaid)
  • Class 6 (mild): Desonide (Desowen)
  • Class 5 (medium): Betamethasone valerate (Betaderm)
  • Class 4 (medium): Mometasone furoate (Elocon)
  • Class 3 (strong): Triamcinolone acetonide (Triderm)
  • Class 2 (strong): Fluocinonide (Lidex)
  • Class 1 (ultra-strong): Clobetasol propionate (Cormax, Temovate)

The Food and Drug Administration (FDA) has only approved the weakest steroid cream, hydrocortisone, as an over-the-counter (OTC) medication. You’ll need a prescription for all other topical steroids.

If you have plaques on sensitive areas, like your face or groin, you’ll probably want to stick with the mild or medium steroid creams.

Stronger steroid creams are typically prescribed for chronic psoriasis that involves very thick plaques. While high-level creams are more powerful, they also pose a higher risk of side effects. Healthcare professionals tend to reserve them for psoriasis plaques that don’t respond to gentler treatment.

Steroid creams can cause changes to your skin like:

Your risk of side effects goes up if you use steroid cream:

  • with a high potency
  • over large surface areas
  • for longer than 3 weeks

Can topical steroids cause adrenal fatigue?

You may have read that chronic corticosteroid use can suppress the amount of natural steroid hormones your body produces and lead to adrenal fatigue, which can cause:

  • weakness
  • low blood pressure
  • lack of appetite

However, adrenal fatigue is mostly a concern for other forms of steroid medication, like injections. That’s because injected or oral steroids have a higher rate of systemic absorption, which means they affect your body overall.

Even high potency steroid creams only rarely affect your adrenal glands. Topical steroids — those absorbed through your skin — only have a minimal effect on your body overall.

How to use topical steroids

Each medication works a little differently, so it’s important to follow the label instructions for your specific cream. If you have a prescription medication, make sure to use the cream exactly as the prescribing clinician directed — and check with them if you have any questions.

That said, here are a few things to keep in mind when using steroid cream:

  • Apply regularly: Depending on the cream, you may need to apply it one to four times a day. Try to put it on at roughly the same time each day.
  • Start small: You only need enough cream to make a thin layer over the psoriasis plaque. Rub it in gently.
  • Only cover the plaques: Your regular skin doesn’t need thinning as a thick plaque does, so avoid rubbing the cream into your healthy skin.
  • Only wrap if your doctor tells you: Covering your psoriasis plaques with a bandage or cloth can help the cream soak in better. But they might also spread the cream to healthy skin, so you’ll want to check with your doctor before wrapping your skin.
  • Check with your doctor if you don’t notice an improvement: With most prescription steroid creams, you should notice some improvement in about a week — but if your symptoms don’t improve within about 2 weeksTrusted Source, you may want to check in with your doctor. If you’re using an OTC cream, it may take a little longer to notice the results.
FYI

If you’ve used a steroid cream for a long time and want to stop, your doctor may taper you off the medication. This means they’ll lower your dose gradually to prevent your psoriasis from flaring up in response to the sudden absence of medication.

Since steroid creams affect your immune system, they may not be the best option if you’re currently recovering from an infection or living with an immunodeficiency disorder.

Your primary care doctor or other healthcare professional may also recommend non-steroid psoriasis treatments if you live with certain endocrine disorders, like Cushing syndrome.

Other treatments for psoriasis include:

  • Vitamin D analogues: topical oils and ointments made of synthetic vitamin D
  • Tar soap: soap made from pine tree resins or coal by-products
  • Salicylic acid: a chemical exfoliant found in OTC face washes and creams that can slough off dead skin cells
  • Methotrexate: a tablet or injection that suppresses your immune response
  • Cyclosporine: another immune suppressant you can take orally or via injection
  • Retinoids: oral or topical medications made from vitamin A compounds
  • Biologics: medications made from living organisms that can block proteins that cause inflammation
  • Phototherapy: a skin treatment that uses controlled exposure to UV light
  • Laser therapy: lasers that target small areas of skin to destroy unhealthy cells

Your doctor may recommend combining steroid creams with other approaches to develop a treatment program that’s right for your specific psoriasis symptoms.

Steroid creams are one of the most common topical treatments for psoriasis.

While they can have powerful anti-inflammatory effects, they may also cause acne and skin discoloration or thinning if you use them for a long time.

Following your doctor’s directions when using steroid creams to treat psoriasis can minimise your risk of side effects.