Tuesday 27 December 2022

Top 5 Most-Popular Psoriasis Content of 2022

From ajmc.com

This year’s most-popular content on psoriasis include research regarding disparities and socioeconomic factors that impact psoriasis treatment and an interview on shared decision making.

The top 5 most-popular psoriasis content this year includes research into geographical differences in mortality, risk factors associated with psoriasis, and the importance of shared decision-making for better managing of this skin condition.

5. Dr Patrick Burnett on Shared Decision-Making for Moderate to Severe Psoriasis

Patrick Burnett, MD, PhD, FAAD, chief medical officer of Arcutis Biotherapeutics, discussed key clinical recommendations for patients with moderate to severe psoriasis with uncontrolled disease, stressing the importance of having a conversation with patients about their end-goal in treatment, focusing bettering their quality of life.

Burnett also discussed the importance of shared decision-making in treating patients with moderate to severe psoriasis.

Watch the interview.

4. Pulling Apart Methods of Diagnosing Axial Psoriatic Arthritis, Back Pain

Despite the high prevalence of axial disease among patients with psoriatic arthritis, disagreement on definitions caused difficulty in diagnosing axial spondylarthritis and back pain. Furthermore, the researchers of this study found notable differences when comparing psoriatic arthritis with ankylosing spondylitis in terms of intensity of back pain and mobility.

Read the full article.

3. Study Highlights Wide Variation in Mortality of Spondyloarthritis, IBD Across the Globe

Large variations in mortality rates for spondylarthritis and inflammatory bowel disease were found geographically. These variations highlight different disparities and socioeconomic factors that may have affected mortality rates across different regions.

Read the full article.

2. TNF Inhibitors Linked to Higher Risk of Psoriasis in Patients With IBD, RA

Researchers underscored the risk of new-onset psoriasis due to tumour necrosis factor-a (TNF) inhibitor. Patients with immune-mediated inflammatory diseases had a 2-fold risk of new-onset psoriasis, according to the study.

Read the full article.

1. Study Finds Link Between Psoriasis, NAFLD Among US Adult Outpatients

One study found outpatients with psoriasis were at greater risk of developing non-alcoholic fatty liver disease (NAFLD) than those without the skin condition. These findings validated prior research on this subject matter, that had found psoriasis to be linked to several comorbid conditions, including cardiovascular diseases, diabetes, and NAFLD.

Read the full article.

https://www.ajmc.com/view/top-5-most-popular-psoriasis-content-of-2022 

Friday 23 December 2022

How to keep psoriasis under control for a long time

From breakinglatest.news

It mainly affects the skin and is, for this reason, easily recognizable by the typical red patches covered by scales: it is psoriasis. And it doesn’t stop there: chronic, inflammatory and systemic disease, which can in fact present with extra-cutaneous manifestations and be linked to various comorbidities. Still today, however, the people who suffer from it, around 1.5 million in Italy alone, often find themselves having to change their therapy as they are unable to keep it under control or to turn off the inflammation, with cumulative damage and a significant impact also on the their quality of life. 

In recent years, however, advances in scientific research are yielding promising results, shedding light on therapeutic solutions capable of keeping inflammation blocked over time by reaching Pasi 100, which occurs when a patient’s skin is completely cleansed and as a result, the risk of cumulative damage to other organs is reduced. In other words, having the availability of drugs capable of reaching the Pasi 100 means having tools that can improve the health and quality of life of patients with psoriasis, as well as improve the sustainability of the healthcare system. Among these tools is bimekizumab, a monoclonal antibody, approved in the European Union for the treatment of plaque psoriasis in adults, capable of selectively inhibiting interleukins 17A and 17F, important in driving inflammatory processes.

The latest data from the open-label extension (Ole) Be Bright study, a multicentre trial evaluating the safety, tolerability and long-term efficacy of bimekizumab, showed that this drug has demonstrated long-lasting efficacy, with a Pasi response 100 maintained after three years in 82% of cases. In addition, approximately 92% of patients who achieved complete skin clearance at week 16 reported little or no impact of the disease on their lives up to three years. “The goal of psoriasis treatment is often complete skin clearance, and the availability of long-term data on various treatment options is important, as it allows healthcare professionals and patients to be better informed when making treatment decisions ”, clarifies Bruce Strober, professor of dermatology at Yale University.

While on the one hand the new data demonstrate that bimekizumab has rapid and lasting efficacy, thus improving the quality of life in the majority of patients with psoriasis, on the other it is urgent to direct the Institutions and the Government towards new health policy measures that ensure patients the right to the best course of care. It is precisely for this reason that the first Italian Alliance for patients with psoriasis was born, which includes the scientific societies Apiafco, Sidemast and Adoi and Salutequità, a laboratory for the analysis, innovation and change of health and social policies. The objectives of the Alliance are contained in the initiative “Call to action: psoriasis, the need does not hide”, which is developed in six key points.

Among these, for example, is the request to include psoriasis, in its various forms, in the National Chronicity Plan and to update “the guidelines on psoriasis, with the identification of recommendations capable of leading to an optimal management of patients,” reads the document. “Today we clinicians have tools and therapies which, thanks to innovation, allow us to counteract psoriasis with positive levels of response that were unthinkable until a few years ago”, comments Ketty Peris, president of Sidemast. “It is unacceptable that such an important greater therapeutic potential could be largely compromised by organizational and management deficiencies which could be overcome by following up on requests from both patients and the scientific community”.

https://www.breakinglatest.news/health/how-to-keep-psoriasis-under-control-for-a-long-time/

Wednesday 21 December 2022

Soap for Psoriasis: All You Need to Know

From healthline.com

Psoriasis causes new skin cells to grow too fast, leaving a chronic build-up of dry, itchy, and sometimes painful skin. Prescription medication can treat the condition, but home management also makes a difference.

One aspect of managing psoriasis at home is considering which soaps and shampoos you use. Some may actually help you relieve dryness and itchiness — or at the very least help you avoid making them worse.

However, not all at-home products work in the same way. Here are some types of soap and shampoo to consider, along with expert tips about products that are good for skin with psoriasis.

You may want to try managing your psoriasis symptoms with tar. But there are a few things to know before you speak with your doctor or head to the pharmacy.

Wood tar soaps and coal tar soaps

There are two types of tar: one made from wood and one made from coal. The one from coal is the kind people most commonly use to help reduce psoriasis symptoms.

You can get shampoo or soap with tar already in it, or you can get a solution that you add to your soap or shampoo.

Tar also comes in different concentrations. In lower concentrations, you can get it without a doctor’s prescription. In higher concentrations, you’ll need a prescription.

Your doctor may prescribe it by itself or as part of a treatment plan with other medications or therapies.

Benefits

Tar can be effective at relieving the symptoms of itching, scaling, and plaques that psoriasis can cause. It’s a substance you can use to help reduce your symptoms long term.

Some people who use it consistently see symptoms clear away for prolonged periods of time. It can be very effective for difficult to manage psoriasis, especially on the scalp.

In lower concentrations, often when it’s an additive in soaps or shampoos, you may find that it’s cheaper to get it over the counter (OTC) than the cost of prescribed medication.

Risks

Even though products containing tar usually indicate how much tar they contain on the label, this doesn’t always accurately reflect how well the product may help reduce your symptoms.

Studies have found that some products containing only 1 percent coal tar extract are more effective than other products containing 5 percent coal tar extract. So, when you buy a random product with tar, you risk not getting the best results.

That’s why it’s a good idea to ask a doctor for specific product recommendations, even if you plan to purchase OTC.

In addition, there are some safety considerations before using tar:

  • If you’re pregnant or nursing, you should avoid it.
  • If you’re more sensitive to ultraviolet (UV) light, you should avoid it. Even if you’re not, you should limit your time outdoors for 24 hours after using it, as it increases your sun sensitivity.
  • There’s some evidence that, in extremely high doses, tar may cause cancer. Usually, this involves people who are exposed to tar in industrial settings. There’s no evidence that OTC products with low tar concentrations are carcinogenic. But if you’re worried, a regular skin cancer check-up may help ease your mind.
  • If you use tar on your scalp, it may make your hair brittle and dry.

Stop use immediately and tell your doctor if you experience:

  • worsening of your psoriasis symptoms
  • extreme burning
  • itching
  • swelling

These can be signs of allergic reaction.

When you exfoliate your skin, you peel away the top layer. This helps your skin heal and rejuvenate faster.

In the case of psoriasis, one common agent that can help you do this is soap or shampoo that contains salicylic acid. You can find many types OTC.

Salicylic acid is a keratolytic, which means it helps the outer layer of your skin shed. It’s a common way to help manage psoriasis symptoms, but it can come with some side effects.

Like coal tar, it can cause some skin irritation. It can also weaken your hair and lead to some hair loss. Talk with your doctor first to make sure it’s right for you.

Colloidal oatmeal, which is just finely ground oats, is a common ingredient in many skin care products.

People use oatmeal to protect their skin and relieve symptoms of different skin conditions. Research shows that oatmeal can be effective because of its anti-inflammatory properties.

You can buy oatmeal soap or shampoo in a pharmacy, which has added oatmeal as an ingredient. You can also get colloidal oatmeal powder and add it to your bath.

This may be a good natural alternative if you cannot use other products to help manage your symptoms.

Although dry skin by itself does not cause psoriasis, experts generally agree that those who have psoriasis should steer clear of products that can dry out or irritate skin.

“Anything gentle and moisturizing is best, and it’s important to moisturize as soon as possible after bathing,” says Dr. Robin Evans, a dermatologist in Stamford, Connecticut.

The American Osteopathic College of Dermatology (AOCD) recommends the following soap brands:

  • Dove
  • Olay
  • Basis

If you have the option, you may want to use cleansers instead. Good choices include:

  • Cetaphil Gentle Skin Cleanser
  • CeraVe Hydrating Cleanser
  • Aquanil Cleanser

Other gentle cleansing agents to consider include:

  • sodium laureth sulfate
  • sodium lauroyl glycinate
  • soybean oil
  • sunflower seed oil

“All of these would help cleanse psoriatic skin with little risk of over-drying,” says Dr. Daniel Friedmann, a dermatologist at Westlake Dermatology in Austin, Texas.

Soaps and lotions that help manage psoriasis symptoms may contain similar ingredients, such as colloidal oatmeal or salicylic acid. Some lotions may contain topical steroids, like hydrocortisone, which also help reduce inflammation.

But the biggest difference is that you rinse off soap after applying it. Meanwhile, a lotion is something you need to leave on your skin to be effective.

Try to follow these tips when using soaps, shampoos, or lotions for psoriasis:

  • Limit your showers to 5 minutes and baths to 15 minutes.
  • Moisturise within 5 minutes of your shower or bath.
  • Try to stick to products intended for psoriasis or products that do not contain ingredients that may make your symptoms worse.
  • Avoid washcloths or loofahs, and dry off gently.

One thing to consider: If you want to use lotions, especially after bathing, you may want to use a cream or ointment instead.

According to the Institute for Quality and Efficiency in Health Care, lotions may be less effective at keeping your skin moisturized than creams or ointments. In fact, ointments contain the most lipids, which help form a protective layer around your skin to retain moisture.

Ask your doctor if a lotion, cream, or ointment is right for you.

Dr. Jessica Kaffenberger, a dermatologist at The Ohio State University Wexner Medical Centre, notes that unmanaged psoriasis can lead to systemic inflammation and potentially increase the risk of developing other conditions, such as:

  • high blood pressure
  • diabetes
  • depression
  • liver disease

“Scalp psoriasis may lead to persistent itching and scalp sensitivity, which may interfere with normal activities,” Friedmann adds.

So, the earlier you begin to manage symptoms consistently, the better. Speaking with your dermatologist regularly for the most up-to-date product recommendations is a good idea.

Choosing the right soaps and shampoos may be just one part of your symptom management plan, but it can play an important role in easing your psoriasis symptoms.

Ingredients to look for

The ingredients in your psoriasis management products are going to depend on the type of psoriasis you have and your symptoms. Before you make a selection, you may want to talk with your doctor.

In addition to the ingredients we already discussed, you can also look for soaps or shampoos with the following: 

  • Lactic acid, urea, and phenol. These ingredients also help remove scales on the skin.
  • Anti-itch ingredients. These ingredients, like calamine, hydrocortisone, camphor, diphenhydramine hydrochloride (HCl), benzocaine, and menthol, can help with itching. However, they may dry out and irritate skin.
  • Aloe vera, jojoba, zinc pyrithione, and capsaicin. These ingredients help moisturize and soothe skin. However, it’s important to test them on a small patch of skin and stop using them if you experience irritation.
  • Epsom and Dead Sea salts. Add these to your bath to help remove scales and reduce itch.

When it comes to scalp psoriasis that includes dandruff, you can look for salicylic acid as well as “sulfur or zinc ingredients to help with the flaking and itching,” says Dr. Kelly M. Cordoro, a member of the Society of Paediatric Dermatology.

Anti-dandruff shampoos, like Head & Shoulders or Selsun Blue, can also work well, adds Dr. Kaffenberger.

She also recommends medicated shampoos, such as:

  • ketoconazole shampoo
  • ciclopirox shampoo
  • steroid shampoos, like clobetasol shampoo

The National Psoriasis Foundation recommends the following shampoo brands to help ease the discomfort of psoriasis on the scalp:

  • MG217 Medicated Conditioning Shampoo, Coal Tar Formula
    • Active ingredient: 3 percent coal tar
  • Neutrogena T/Gel Therapeutic Shampoo, Stubborn Itch
    • Active ingredient: 0.5 percent coal tar
  • Dermarest Psoriasis Medicated Shampoo + Conditioner
    • Active ingredient: 3 percent salicylic acid

More National Psoriasis Foundation Seal of Recognition products are available on psoriasis.org.

Ingredients to avoid

Many ingredients in soaps and shampoos assist with the spa-like enjoyment of cleansing the body, but there are some that might not be great for people who have psoriasis.

You may want to avoid products with fragrances or dyes, as these can irritate the skin or even cause allergic reaction.

The Annex III of the European Union Cosmetics Directive listed the 26 most common cosmetic fragrance additive allergens for your reference.

Alcohol is also an ingredient that can inflame the skin, Kaffenberger adds.

Alcohol can often be listed on a label as:

  • lauryl alcohol
  • myristyl alcohol
  • cetearyl alcohol
  • cetyl alcohol
  • behenyl alcohol

You may want to avoid products that contain preservatives, like:

  • parabens
  • formaldehyde
  • butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT)

A key part of managing your psoriasis successfully is understanding which products work best for your symptoms. This includes the type of soap and shampoo you use, as well as the type of moisturizing lotion or ointment.

With so many prescription and OTC options available, and so many ingredients, you may find it hard to know what to choose. Organizations, like the American Academy of Dermatology or the National Psoriasis Foundation, can provide resources.

https://www.healthline.com/health/psoriasis/soaps-and-shampoo-options?slot_pos=article_1&utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=psoriasis&utm_content=2022-12-20&apid=39239719&rvid=058431b717dcfa59c0cdd27cd0a9313769e8b3dd4ad59d88efd0ded7ddb4774e 

Thursday 15 December 2022

Psoriatic Arthritis: How To Recognize It?

From emergency-live.com 

It can sometimes be difficult to distinguish psoriatic arthritis from other conditions since the occurrence of joint pain is a common symptom of many rheumatologic conditions.

Here’s how to recognize it.

What is psoriatic arthritis

Psoriatic arthritis is a chronic autoimmune inflammatory disease that affects the joints of people with psoriasis (usually 3 out of 10 people).

The immune system of these people views the normal components of the joint as a threat by triggering an inflammatory process directed primarily against the synovial membrane, connective tissue, and bone.

This inflammatory mechanism can severely damage the joint, going so far as to impair the function of the affected joint, especially if left untreated.

Psoriatic arthritis: the symptoms

Psoriatic arthritis can appear rather insidiously with nuanced symptomatology common to many other rheumatic diseases such as rheumatoid arthritis or gout.

Typically, it manifests as pain, swelling, redness, and heat in the joints especially of the hands, feet, knees, and ankles but inflammation can also affect the neck, shoulders, wrists, and hips.

In addition to affecting tendons, ligaments, synovial bursa, and joint nails, psoriatic arthritis may be accompanied by feelings of fatigue, exhaustion, and prolonged morning stiffness.


Why does psoriatic arthritis appear?

The causes are still not entirely clear.

Like psoriasis, psoriatic arthritis is multifactorial, due to a combination of:

  • hereditary (genetic) factors that predispose to the disease
  • environmental factors (emotional stress, infections) that can trigger it.

Thus, in a genetically predisposed person, certain environmental factors such as physical trauma, severe emotional stress, taking certain medications, or infection can trigger the disease.

In particular, streptococcal and staphylococcal bacterial infections and HIV infection appear to play a significant role in psoriatic arthritis.

How is the diagnosis made?

There are no specific tests to recognize psoriatic arthritis.

The diagnosis arises from a set of elements that the physician must evaluate, first and foremost the patient’s medical history, followed by observation of symptoms.

Because of this, each person will have symptoms that can vary greatly from others and therefore require individualized advice to better manage the disease over time.

https://www.emergency-live.com/health-and-safety/psoriatic-arthritis-how-to-recognize-it/

Tuesday 13 December 2022

12 Ways to Treat Psoriasis at Home

From healthline.com

Psoriasis is a recurring autoimmune disorder that affects more than 7.5 million American adults. It tends to appear pink or red, usually with silvery-white scales, on those that have fair to light skin tones. On medium skin tones, it may look salmon-coloured with a silvery-white scale, and on darker skin tones, it could look violet and the scale grey. Or it can also appear dark brown and difficult to see.

Even though it affects your skin, psoriasis actually begins inside your body in your immune system.

Psoriasis is a condition where your T-cells, a type of white blood cell, can become overactive to produce other immune markers that can cause an inflammatory reaction on the skin. The reaction on the skin shows up in the form of silvery-white scale, depending on the skin ton

Even though there’s no cure, many treatments exist to ease the symptoms of psoriasis. Here are 12 ways to manage mild symptoms at home.

Dietary supplements may help ease psoriasis symptoms from the inside.

Fish oilvitamin Dmilk thistlealoe veraOregon grape, and evening primrose oil have all been reported to help ease mild symptoms of psoriasis, according to the National Psoriasis Foundation.

Check with your doctor before taking supplements to make sure they don’t interfere with other health conditions you may have or medications you’re taking.

Use a humidifier to keep the air in your home or office moist. This can help prevent dry skin before it starts.

Moisturisers for sensitive skin can keep your skin supple and moisturized.

Aloe vera has been shown in some cases to reduce redness and irritation caused by psoriasis. A 2010 studyTrusted Source found aloe vera gel cream to be slightly more effective in improving psoriasis symptoms compared to 0.1 percent triamcinolone acetonide, a steroid cream used to treat psoriasis.

More research is needed to show for sure if aloe vera can improve symptoms of psoriasis. However, the risk of trying aloe vera gels or creams is low, so it may be worth a try.

Most soaps and perfumes have dyes and other chemicals in them that may irritate your skin. They can make you smell great, but they also can inflame psoriasis.

Avoid such products when you can, or choose those with “sensitive skin” labels.

Diet may play a role in managing psoriasis.

Limiting red meat, saturated fats, refined sugars, carbohydrates, and alcohol may help reduce flare-ups triggered by such foods.

Cold water fish, seeds, nuts, and omega-3 fatty acids are known for their ability to reduce inflammation. This can be helpful for managing psoriasis symptoms.

Olive oil may also have soothing benefits when applied topically to the skin. Try massaging a few tablespoons on your scalp to help loosen troublesome plaques during your next shower.

A lukewarm bath with Epsom salt, mineral oil, milk, or olive oil can soothe the itching and infiltrate scales and plaques. Oatmeal baths can also be very helpful and soothing for plaque psoriasis.

Be sure that the water is not hot. Hot water can cause more irritation.

Moisturise immediately after your bath for double benefits.

Light therapy involves exposing your skin to ultraviolet light under the supervision of a doctor.

Ultraviolet light can help slow the growth of skin cells triggered by psoriasis. This therapy often requires consistent and frequent sessions. Sitting in the sun for 10 to 15 minutes can also help reduce plaques.

However, too much sunlight and tanning beds aren’t the best options as they can also increase your risk of skin cancer.

Light therapy should always be done under the supervision of a doctor.

Any chronic condition like psoriasis can be a source of stress, which in turn can worsen psoriasis symptoms.

In addition to reducing stress whenever possible, consider incorporating stress-reducing practices such as yoga and meditation. 

Alcohol is a trigger for many people who have psoriasis.

study in 2015 found an increased risk of psoriasis among women who drank nonlight beer. Those who drank at least five nonlight beers per week were nearly twice as likely to develop psoriasis compared to women who didn’t drink.

Herbs are commonly used to treat many conditions.

Turmeric has been found to help minimize psoriasis flare-ups. It can be taken in pill or supplement form, or sprinkled on your food.

Talk to your doctor about the potential benefits for you.

Avoid tobacco. Smoking may increase your risk of psoriasis.

If you already have psoriasis, it can make your symptoms more severe.

Being overweight or obese puts you at a greater risk of developing psoriasis. Obesity is also associated with more severe psoriasis symptoms. StudiesTrusted Source have found that losing weight can help improve these symptoms.

Here are some tips for losing weight:

  • exercise on a regular basis
  • cut back on refined carbs
  • eat plenty of vegetables and protein

There isn’t a single answer for keeping the symptoms of psoriasis at bay. What works for one person may not work for another.

Some treatment options may have negative side effects for pre-existing conditions other than psoriasis.

While these remedies for psoriasis may help with mild cases, prescription therapy is required for more severe cases. Talk to your doctor before seeking treatment on your own.

A dermatologist can treat the thick, red, scaly patches of skin (also known as plaques) from psoriasis. They can also treat other parts of your body that moderate to severe psoriasis may affect, such as your scalp and nails. Consider checking with your dermatologist when you experience a flare or worsening symptoms.

Nearly a third of people with psoriasis develop a condition called psoriatic arthritis. This can cause swollen, stiff, or painful joints. A rheumatologist can determine if you have psoriatic arthritis and prescribe treatments to control your symptoms. This type of doctor specializes in treating arthritis and other musculoskeletal disorders.

Psoriasis has been linked to other health conditions, such as lymphoma, heart disease, diabetes, and high blood pressure. A primary care doctor can help you find ways to reduce your risk of other conditions and improve your overall health. They can also screen you for early warning signs of psoriasis complications and refer you to a specialist, if necessary.

While psoriasis has no cure, it can be treated with a variety of prescription medications (like immunosuppressive drugs) and over-the-counter drugs (such as topical ointments). A pharmacist can provide information and tips on following your treatment plan and can make sure your medications are safe to take together. They can also answer questions or address concerns about your medications.

Stress has been shown to be a trigger for psoriasis flares. A psychologist, licensed professional counsellor, or clinical social worker can help you develop personalized ways to manage stress. Self-care techniques — such as breathing exercises, journaling, meditation, yoga, and stretching — can also help you ease stress.

Cutting back on foods that trigger psoriasis flares can help reduce symptoms. A dietitian can help you develop a nutritious eating plan that may potentially reduce inflammation in the body. They can also help you maintain a healthy weight to avoid obesity and reduce your risk of psoriasis-related complications, such as diabetes and heart disease.

https://www.healthline.com/health/psoriasis/treat-symptoms-home?slot_pos=article_1&utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=psoriasis&utm_content=2022-12-13&apid=39239719&rvid=058431b717dcfa59c0cdd27cd0a9313769e8b3dd4ad59d88efd0ded7ddb4774e